The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle
[8].
The Pineal Gland Has Highest Levels of Fluoride in Body. As a calcifying tissue that is exposed to a high volume of blood flow, the pineal gland is a major target for fluoride accumulation in humans. In fact, the calcified parts of the pineal gland (hydroxyapatite crystals) contain the highest fluoride concentrations in the human body (up to 21,000 ppm F), higher than either bone or teeth
[9].
A study measuing sleep patterns
[10] showed an increase of fluoride in the body was associated with 1.97 times higher odds of reporting symptoms suggestive of sleep apnea (95% CI: 1.27, 3.05, p=0.02), 24 min later bedtime (95% CI: 0.10, 0.70; 0.05), a 26 min later morning wake time (B=0.43, 95% CI: 0.13, 0.73; p=0.04), and among males, a 38% reduction in the odds of reporting snoring (95% CI: 0.45, 0.87, p=0.03).